Description

5-Hydroxytryptamine-B-14C Creatinine is a radiolabeled compound specifically designed for advanced research and analytical applications. This product is critical for conducting precise metabolic, pharmacokinetic, and tracer studies, offering researchers a reliable tool for tracking and quantification. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on neuroscience, biochemistry, and drug development.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the metabolism and biotransformation of serotonin-related compounds in biological systems.
• Pharmacokinetic Studies: Essential for determining the absorption, distribution, metabolism, and excretion (ADME) profiles of novel therapeutic agents in preclinical research.
• Biochemical Research: Serves as a key reagent in enzyme assays and receptor binding studies to investigate serotoninergic pathways and related mechanisms.
• Drug Development: Supports the development and validation of analytical methods (e.g., LC-MS, HPLC) for quantifying drug candidates and their metabolites.
• Quality Control Reference Standard: Acts as an internal standard or reference material in analytical laboratories to ensure accuracy and reproducibility in testing.

Basic Information

Product Name	5-Hydroxytryptamine-B-14C Creatinine
CAS No.	141983-95-1
Molecular Formula	C₁₄H₁₈N₄O₂ (with 14C label)
Molecular Weight	~274.32 g/mol (unlabeled)
Synonyms	Serotonin-B-14C Creatinine; 5-HT-B-14C Creatinine; [14C]-Labeled 5-Hydroxytryptamine Creatinine Complex; 3-(2-Aminoethyl)-1H-indol-5-ol-B-14C Creatinine Salt; Radiolabeled Serotonin Creatinine Sulfate (14C); 5-Hydroxytryptamine (14C) Creatinine Sulfate
EINECS	Contact for details

Quality Control

Every batch of 5-Hydroxytryptamine-B-14C Creatinine is manufactured and tested under strict quality management systems. We ensure high specific activity and radiochemical purity through advanced analytical techniques including HPLC and radio-HPLC. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the specific activity, radiochemical purity, chemical purity, and solvent content. Our quality commitment aligns with the standards expected for research-grade radioactive materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider conditions recommended for radiolabeled compounds to maintain stability and specific activity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 95%
Chemical Purity (HPLC)	≥ 98%
Solvent Content (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.