Description

(Asp(3)-Admaadda(5))Microcystin-Lhar is a specific structural variant of the potent hepatotoxin microcystin, a cyclic peptide produced by certain freshwater cyanobacteria. This compound is of critical importance for research and analytical applications, serving as a precise reference standard for the detection and quantification of microcystin congeners in environmental and biological samples. It is primarily needed by analytical laboratories, environmental monitoring agencies, and research institutions focused on water safety, toxicology, and the development of diagnostic assays.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the calibration of analytical instruments such as HPLC-MS/MS and ELISA kits.
• Environmental Monitoring: Quantification and confirmation of microcystin-LR analogs in drinking water, recreational water bodies, and algal bloom samples.
• Toxicological Research: Investigation of the specific mechanisms of toxicity, protein phosphatase inhibition, and hepatotoxic effects of microcystin variants.
• Method Development & Validation: Essential for developing, optimizing, and validating new analytical methods for cyanotoxin detection with high specificity and accuracy.
• Quality Control & Assurance: Used in laboratory proficiency testing and as an internal standard to ensure the reliability and reproducibility of testing data.
• Regulatory Compliance Testing: Supports testing to meet guidelines set by organizations like the WHO, EPA, and other global water quality regulatory bodies.

Basic Information

Product Name	(Asp(3)-Admaadda(5))Microcystin-Lhar
CAS No.	141663-36-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Microcystin-Lhar (Asp3-Adda5); [Asp3,Adda5]Microcystin-LR; Microcystin variant LR (Asp3, Adda5); 3-Aspartic acid-5-(2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl microcystin-LR; Cyanobacterial toxin analog; Microcystin-LR congener; ADDA-containing cyclic heptapeptide
EINECS	Contact for details

Quality Control

Our high-purity (Asp(3)-Admaadda(5))Microcystin-Lhar is produced and handled under strict quality protocols suitable for research and analytical applications. Each batch undergoes rigorous identity confirmation and purity analysis using advanced techniques such as HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chromatographic data, and storage conditions is provided with every shipment to ensure traceability and data integrity for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms to reference
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.