Description

(Ser(1)-Admadda(5))Microsystin-Lr CAS NO 141634-76-6 is a specific cyclic peptide congener of the potent hepatotoxin microcystin, a class of compounds produced by certain freshwater cyanobacteria. This high-purity reference material is critical for environmental monitoring, toxicological research, and the development of accurate diagnostic assays. It is primarily utilized by analytical laboratories, research institutions, and regulatory bodies focused on water safety and cyanotoxin risk assessment.

Application

• Analytical Reference Standard: Primary use as a certified standard for the quantitative analysis of microcystins in water samples via HPLC, LC-MS/MS, and ELISA techniques.
• Toxicological Research: Essential for studying the mechanisms of hepatotoxicity, inhibition of protein phosphatases, and the long-term health effects of cyanotoxin exposure.
• Method Development & Validation: Used to develop, calibrate, and validate new analytical methods for the detection and quantification of microcystin variants in complex matrices.
• Quality Control & Assurance: Serves as a system suitability check and positive control in laboratory quality control protocols for water testing facilities.
• Regulatory Compliance Testing: Supports testing to comply with national and international guidelines for cyanotoxin levels in drinking and recreational water (e.g., WHO, EPA).
• Biochemical Studies: Tool for investigating enzyme inhibition kinetics and the structural activity relationships within the microcystin family.

Basic Information

Product Name	(Ser(1)-Admadda(5))Microsystin-Lr
CAS No.	141634-76-6
Molecular Formula	C49H74N10O12
Molecular Weight	995.2 g/mol
Synonyms	Microcystin-LR variant; [Ser1, Admadda5]Microcystin-LR; 3-Desmethyl-3-(2-methyl-3-methoxypropyl)-microcystin-LR; ADMAdda-microcystin-LR; Cyanoginosin-LR analog; Microcystin congener; Cyclic heptapeptide toxin; Cyanobacterial hepatotoxin reference material
EINECS	Contact for details

Quality Control

Every batch of (Ser(1)-Admadda(5))Microsystin-Lr is produced and analyzed under strict quality management protocols. Identity and purity are confirmed through a combination of advanced chromatographic and spectroscopic techniques, including HPLC, LC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing batch-specific purity, chromatographic data, and storage recommendations is provided with each shipment to ensure traceability and support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95% (Area % at 238 nm)
Water Content (KF)	≤ 3.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.