Description

Reboxetine·Methanesulfonic Acid is the mesylate salt form of the selective norepinephrine reuptake inhibitor (NRI) Reboxetine. This compound is of significant value as a key pharmaceutical intermediate or reference standard in the research and development of antidepressant medications. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in the synthesis of active pharmaceutical ingredients (APIs) and quality control processes for neuropharmacological agents.

Application

• Pharmaceutical Intermediate: Critical starting material or intermediate in the synthesis of Reboxetine API.
• Reference Standard: Used for analytical method development, validation, and quality control (HPLC, LC-MS) in pharmaceutical manufacturing.
• Research & Development: Serves as a standard in preclinical and clinical studies investigating norepinephrine reuptake inhibition.
• Active Pharmaceutical Ingredient (API) Manufacturing: Direct use in the formulation of finished dosage forms after further processing and purification.
• Metabolite Studies: Utilized in the identification and quantification of drug metabolites during pharmacokinetic research.

Basic Information

Product Name	Reboxetine·Methanesulfonic Acid
CAS No.	141425-90-3
Molecular Formula	C19H23NO3 · CH4O3S
Molecular Weight	409.50 g/mol
Synonyms	Reboxetine Mesylate; Reboxetine Methanesulfonate; (R*,R*)-2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine methanesulfonate; FCE 20124 mesylate; Edronax (mesylate salt); (R,R)-Reboxetine mesylate; (2R,αR)-2-[(2-Ethoxyphenoxy)benzyl]morpholine methanesulfonate
EINECS	Contact for details

Quality Control

Our Reboxetine·Methanesulfonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting specifications suitable for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.