Description

Celgosivir Hydrochloride is a potent and selective α-glucosidase I inhibitor, a key compound in antiviral and glycobiology research. Its primary value lies in its ability to interfere with the N-linked glycosylation pathway of viral envelope proteins, making it a crucial tool for studying host-directed antiviral strategies. This high-purity active pharmaceutical ingredient (API) is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on virology, infectious diseases, and metabolic disorder therapeutics.

Application

• Antiviral Research: Investigation of host-directed therapies against viruses such as dengue, hepatitis B and C, and influenza by inhibiting viral glycoprotein maturation.
• Glycobiology Studies: A critical research tool for studying N-linked oligosaccharide processing and endoplasmic reticulum α-glucosidase function.
• Pharmaceutical Development: Serves as a key starting material or intermediate in the synthesis of novel therapeutic agents targeting viral infections.
• Biochemical Assays: Used as a reference standard or inhibitor in enzymatic assays to study glycosidase activity and carbohydrate metabolism.
• Preclinical Studies: Evaluation of efficacy and mechanism of action in cellular and animal models of viral diseases and metabolic disorders.

Basic Information

Product Name	Celgosivir Hydrochloride
CAS No.	141117-12-6
Molecular Formula	C₁₀H₁₉NO₄ • HCl
Molecular Weight	253.72 g/mol (free base: 217.26 g/mol)
Synonyms	6-O-Butanoylcastanospermine Hydrochloride; MDL 28574; BCS 20625; Castanospermine 6-Butanoate Hydrochloride; (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizine-6-butanoate Hydrochloride; Celgosivir HCl; Butanoylcastanospermine HCl
EINECS	Contact for details

Quality Control

Our Celgosivir Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets high-grade research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0% (anhydrous basis)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.