Description

Pentanedioic Acid, 3-Phenyl-, Monoethyl Ester, (3R)- (9Ci) is a chiral, non-racemic organic compound belonging to the class of substituted glutaric acid monoesters. This material matters as a versatile chiral building block and intermediate, offering a defined stereocenter for the synthesis of complex molecules with specific three-dimensional architectures. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in stereoselective reactions to construct enantiomerically pure compounds.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis, such as hydrogenation or cross-coupling reactions.
• Fine Chemical Production: Incorporated into the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Item	Details
Product Name	Pentanedioic Acid, 3-Phenyl-, Monoethyl Ester, (3R)- (9Ci)
CAS No.	140863-09-8
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	(3R)-3-Phenylglutaric Acid Monoethyl Ester; Monoethyl (3R)-3-Phenylglutarate; Ethyl (3R)-3-Phenyl-5-oxo-5-pentanoate; (R)-3-Phenylglutaric Acid Monoethyl Ester; 3-Phenylglutaric Acid Monoethyl Ester, (R)-; Ethyl Hydrogen (3R)-3-Phenylglutarate; (R)-Monoethyl 3-Phenylglutarate
EINECS	Contact for details

Quality Control

Our production of Pentanedioic Acid, 3-Phenyl-, Monoethyl Ester, (3R)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.