Description

11-Hydroxy-8,9-Epoxyeicosatrienoic Acid is a specialized eicosanoid derivative, a key metabolite in the arachidonic acid cascade. This compound is significant for its role as a bioactive lipid mediator involved in critical physiological and pathophysiological signaling pathways. It is primarily utilized by researchers and developers in the pharmaceutical and life sciences sectors for advanced biochemical studies, drug discovery, and the development of analytical standards.

Application

• Biochemical Research: Used as a high-purity reference standard and analytical reagent in lipidomics and eicosanoid research.
• Pharmaceutical R&D: Serves as a critical intermediate or target molecule in the investigation of inflammation, cardiovascular, and renal disease pathways.
• Enzyme Activity Studies: Employed as a substrate or product in assays for cytochrome P450 (CYP) epoxygenase and soluble epoxide hydrolase (sEH) activity.
• Cell Signaling Research: Applied in studies to elucidate the mechanisms of action of epoxy fatty acids and their hydroxylated derivatives in cellular models.
• Diagnostic Development: Potential use in the calibration and development of diagnostic assays for specific lipid mediators.

Basic Information

Product Name	11-Hydroxy-8,9-Epoxyeicosatrienoic Acid
CAS No.	140460-58-8
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	11-Hydroxy-8,9-epoxy-5Z,14Z-eicosatrienoic acid; 11-Hydroxy-8,9-EET; 11-OH-8,9-EET; 8,9-Epoxy-11-hydroxy-5Z,14Z-eicosatrienoic acid; 11(R/S)-Hydroxy-8,9-epoxyeicosatrienoic acid; 11-HETE-8,9-epoxide; 11-Hydroxy-8,9-epoxy-5,14-eicosadienoic acid
EINECS	Contact for details

Quality Control

Our 11-Hydroxy-8,9-Epoxyeicosatrienoic Acid is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic and light-sensitive nature, the material should be handled in a controlled environment and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.