Description

Milameline CAS NO 139886-32-1 is a high-purity pharmaceutical intermediate and research chemical of significant interest in neuropharmacology. This compound matters for its role in the development of novel therapeutic agents targeting cognitive function and neurological pathways. It is primarily needed by pharmaceutical R&D departments, contract research organizations (CROs), and academic institutions engaged in neuroscience and drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) for neurological research.
• Cognitive Research: Used in preclinical studies investigating muscarinic receptor agonists for potential applications in cognitive disorders.
• Neuropharmacology Studies: Serves as a reference standard and experimental compound in academic and industrial research on cholinergic systems.
• Drug Discovery & Development: Employed in high-throughput screening and lead optimization phases for central nervous system (CNS) targets.
• Reference Material: Utilized as an analytical standard in method development and quality control for related pharmaceutical products.

Basic Information

Product Name	Milameline
CAS No.	139886-32-1
Molecular Formula	C17H23NO3
Molecular Weight	289.37 g/mol
Synonyms	Milameline; (3aR,4S,9bS)-4-(Hexyloxy)-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindol-1-one; 4-(Hexyloxy)-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindol-1-one; CI-979; PD-129409; LY-246708; Talsaclidine (related compound)
EINECS	Contact for details

Quality Control

Our Milameline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.