Description

D-[5-13C]Xylose is a stable isotope-labeled analog of the pentose sugar D-xylose, specifically enriched with carbon-13 at the C-5 position (CAS NO 139657-63-9). This compound is an essential tracer in metabolic research, enabling precise tracking and quantification of pentose phosphate pathway (PPP) flux and carbohydrate metabolism in biological systems. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic developers engaged in advanced isotope labeling studies, metabolic flux analysis (MFA), and nuclear magnetic resonance (NMR) spectroscopy.

Application

• Metabolic Flux Analysis (MFA): Used as a 13C-labeled tracer to map and quantify the activity of the pentose phosphate pathway in cells, tissues, or microorganisms.
• NMR Spectroscopy Studies: Serves as a crucial standard and substrate for 13C-NMR to investigate carbohydrate metabolism and enzyme kinetics.
• Biomedical & Pharmaceutical Research: Employed in studies of metabolic disorders, cancer metabolism (Warburg effect), and the development of new therapeutic agents.
• Stable Isotope Labeling: Acts as a building block for the synthesis of more complex 13C-labeled compounds for use in mass spectrometry and other analytical techniques.
• Microbial & Plant Biochemistry: Applied to study xylose utilization pathways in bacteria, yeast, and plants for biofuel and biochemical production research.

Basic Information

Product Name	D-[5-13C]Xylose
CAS No.	139657-63-9
Molecular Formula	C5H10O5 (13C at C-5)
Molecular Weight	151.13 g/mol (for 13C1 isotopologue)
Synonyms	(1-13C)Xylose; D-Xylose-5-13C; Xylose (D-13C1); 5-13C-D-Xylose; D-Xylopyranose-5-13C; Wood Sugar-5-13C; (5-13C)Xylose; [5-13C]-D-Xylose
EINECS	Contact for details

Quality Control

Our D-[5-13C]Xylose is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research applications. Each batch undergoes rigorous quality testing, including isotopic enrichment analysis by NMR and/or MS, and chemical purity assessment by HPLC. Certificates of Analysis (COA) are provided, detailing the isotopic purity (atom % 13C), chemical purity, and specific analytical data.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Isotopic Purity (atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Specific Optical Rotation	+18.5° to +19.5° (c=10 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.