Description

1-(4-Fluorobenzyl)Cyclopropanecarboxylic Acid is a high-purity fluorinated cyclopropane derivative, a crucial building block in modern synthetic organic chemistry. Its unique structure, combining a cyclopropane ring with a fluorinated benzyl group, makes it a versatile intermediate for creating complex molecules with enhanced biological activity and metabolic stability. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Development: Used as a precursor in the creation of advanced pesticides and herbicides, where the fluorine atom and cyclopropane moiety can improve efficacy and environmental profile.
• Ligand and Catalyst Synthesis: Serves as a starting material for constructing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where its rigid structure can influence material properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1-(4-Fluorobenzyl)Cyclopropanecarboxylic Acid
CAS No.	139229-60-0
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]cyclopropanecarboxylic acid; 1-(4-Fluorobenzyl)cyclopropane-1-carboxylic acid; Cyclopropanecarboxylic acid, 1-[(4-fluorophenyl)methyl]-; 1-(p-Fluorobenzyl)cyclopropanecarboxylic Acid; 4-Fluorobenzylcyclopropanecarboxylic Acid; 1-(4-Fluorobenzyl)-1-cyclopropanecarboxylic Acid; (1-((4-Fluorobenzyl)cyclopropyl)formic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.