Description

1-(2,6-Difluorophenyl)Cyclopropanecarboxylic Acid is a high-purity, versatile organic building block characterized by its unique cyclopropane and difluorophenyl structure. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, offering critical structural motifs for modulating biological activity and physicochemical properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the steric influence of the cyclopropane ring.
• Material Science Research: Employed in the synthesis of specialty monomers or polymers for advanced materials with specific optical or electronic properties.
• Chemical Biology Probe: Utilized as a building block for creating molecular probes to study enzyme function or protein-ligand interactions in biochemical research.

Basic Information

Product Name	1-(2,6-Difluorophenyl)Cyclopropanecarboxylic Acid
CAS No.	139229-58-6
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	1-(2,6-Difluorophenyl)cyclopropanecarboxylic acid; 2,6-Difluorophenylcyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 1-(2,6-difluorophenyl)-; 1-(2,6-Difluorophenyl)cyclopropane-1-carboxylic acid; 139229-58-6; 2,6-Difluoro-α-(cyclopropylcarbonyl)benzene; α-(2,6-Difluorophenyl)cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.