Description

Zanamivir Hydrate CAS NO 139110-80-8 is a potent and selective neuraminidase inhibitor, representing a critical class of antiviral agents. Its primary value lies in its ability to effectively treat and prevent infections caused by influenza A and B viruses by blocking the viral enzyme neuraminidase. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing and producing antiviral medications, particularly for inhalation or intranasal delivery systems.

Application

• Primary active ingredient in the formulation of antiviral drugs for the treatment of influenza.
• Key component in the production of dry powder inhalers (DPIs) for targeted respiratory delivery.
• Used in the development of intranasal sprays for the prevention and treatment of flu symptoms.
• Critical raw material for compounding pharmacies preparing specialized antiviral formulations.
• Reference standard in analytical laboratories for quality control and method development of neuraminidase inhibitors.
• Starting material or intermediate in advanced pharmaceutical research for next-generation antiviral therapies.

Basic Information

Product Name	Zanamivir Hydrate
CAS No.	139110-80-8
Molecular Formula	C12H20N4O7
Molecular Weight	332.31 g/mol
Synonyms	Zanamivir; GG167; 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid; 5-Acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid; (2R,3R,4S)-3-Acetamido-4-guanidino-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid; Relenza (Brand Name); GR 121167X; ZAN
EINECS	Contact for details

Quality Control

Our Zanamivir Hydrate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing purity, identity, and impurity profiles to support your regulatory and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 8.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	< 5.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.