Description

Benzoic Acid, 2-Fluoro-5-[(1-Methylethyl)Thio]- is a fluorinated and sulfur-substituted benzoic acid derivative, serving as a versatile and high-value synthetic intermediate in advanced chemical manufacturing. Its unique structure, incorporating both fluorine and a thioether group, makes it a critical building block for creating compounds with tailored electronic, steric, and biological properties. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the thioether and fluorobenzoic acid moiety can contribute to selective activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for synthesizing fluorinated aromatic cores used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) to modify dielectric anisotropy and electron transport properties.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, or specific surface properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to develop novel chelating ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Benzoic Acid, 2-Fluoro-5-[(1-Methylethyl)Thio]-
CAS No.	138736-66-0
Molecular Formula	C10H11FO2S
Molecular Weight	214.26 g/mol
Synonyms	2-Fluoro-5-(isopropylthio)benzoic acid; 5-(Isopropylthio)-2-fluorobenzoic acid; 2-Fluoro-5-[(1-methylethyl)sulfanyl]benzoic acid; 2-Fluoro-5-(propan-2-ylsulfanyl)benzoic acid; Benzoic acid, 2-fluoro-5-[(1-methylethyl)thio]- (9CI); 138736-66-0; 2-Fluoro-5-isopropylsulfanylbenzoic acid
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 2-Fluoro-5-[(1-Methylethyl)Thio]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assay, residual solvent analysis (GC), and identity confirmation (IR, NMR). A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.