Description

(+)-Trimipramine Maleate CAS NO 138283-61-1 is the maleate salt of the dextrorotatory enantiomer of trimipramine, a tricyclic antidepressant (TCA). This high-purity enantiomer is critical for advanced pharmaceutical research and development, particularly in studying stereospecific pharmacological effects. It is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories engaged in neuropharmacology and chiral drug development.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the synthesis and research of enantiomerically pure antidepressant formulations.
• Neuropharmacological Research: A key tool for investigating the specific biological activity, metabolism, and receptor binding profiles of the (+)-enantiomer.
• Chiral Separation Studies: Employed in developing and validating chromatographic methods for enantiomeric purity analysis.
• Biochemical Assays: Used in vitro studies to understand the mechanistic pathways of tricyclic compounds.
• Academic & Institutional Research: Supports fundamental research in medicinal chemistry and psychopharmacology at universities and R&D centers.

Basic Information

Product Name	(+)-Trimipramine Maleate
CAS No.	138283-61-1
Molecular Formula	C23H29N3O4
Molecular Weight	411.50 g/mol
Synonyms	(+)-Trimipramine maleate salt; (R)-Trimipramine maleate; Dextro-Trimipramine maleate; 5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenzo[b,f]azepine maleate (1:1); Surmontil enantiomer; Maleic acid trimipramine salt; Trimipramine (+)-isomer maleate
EINECS	Contact for details

Quality Control

Our (+)-Trimipramine Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets high-grade standards suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.