Description

Benzamide, n-(2-Amino-2-Oxoethyl-2-13C)- (9Ci) is a carbon-13 labeled derivative of glycine benzamide, serving as a crucial stable isotope-labeled building block for advanced research and development. This compound matters for its role in enabling precise metabolic and pharmacokinetic studies through mass spectrometry and NMR spectroscopy. It is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions engaged in drug discovery, biomarker research, and proteomics.

Application

• Pharmaceutical Research: As a stable isotope-labeled internal standard for the accurate quantification of drug candidates and metabolites in bioanalytical LC-MS/MS methods.
• Metabolic Pathway Tracing: Used in tracer studies to investigate glycine-related biochemical pathways and amino acid metabolism in vivo.
• Proteomics & Biomarker Discovery: Incorporation into peptides or probes for mass spectrometry-based protein quantification and identification strategies (e.g., SILAC).
• NMR Spectroscopy: Provides a non-radioactive, stable isotopic label (13C) for structural elucidation and dynamic studies of biomolecules.
• Chemical Synthesis Intermediates: Serves as a specialized synthon for the preparation of more complex 13C-labeled compounds for research purposes.

Basic Information

Product Name	Benzamide, n-(2-Amino-2-Oxoethyl-2-13C)- (9Ci)
CAS No.	137248-42-1
Molecular Formula	C8H813CN2O2
Molecular Weight	166.62 g/mol (for 13C1 isotopologue)
Synonyms	2-Benzamidoacetamide-2-13C; N-(Carbamoylmethyl-2-13C)benzamide; Glycine benzamide-2-13C; (2-Amino-2-oxoethyl-2-13C)benzamide; Benzamidoacetamide-2-13C; N-(2-Amino-2-oxoethyl-2-13C)benzamide; Stable Isotope Labeled Benzamide Derivative; 13C1-Glycine Benzamide
EINECS	Contact for details

Quality Control

Every batch of our carbon-13 labeled Benzamide is produced and tested under strict quality protocols to ensure isotopic purity and chemical integrity, which are critical for research reproducibility. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (Atom % 13C), chemical purity, and identity confirmation. Our quality system supports compliance with the stringent requirements of pharmaceutical R&D and analytical reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	13C NMR spectrum confirms labeling at position 2
Purity (HPLC)	≥ 98.0% (Chemical Purity)
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.