Description

2,4,5-Trifluoro-3-Hydroxybenzoic Acid Methyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is critical for modulating biological activity and stability. It is primarily needed by R&D chemists and process development teams working on active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of fluorinated drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where fluorination enhances efficacy and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and electron-transport materials.
• Chemical Research & Development: A versatile reagent for exploring new fluorination methodologies and constructing complex aromatic scaffolds in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2,4,5-Trifluoro-3-Hydroxybenzoic Acid Methyl Ester
CAS No.	137234-92-5
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	Methyl 2,4,5-trifluoro-3-hydroxybenzoate; 3-Hydroxy-2,4,5-trifluorobenzoic acid methyl ester; Benzoic acid, 2,4,5-trifluoro-3-hydroxy-, methyl ester; 2,4,5-Trifluoro-3-hydroxy-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2,4,5-Trifluoro-3-Hydroxybenzoic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the rigorous standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.