Description

(R,R)-2,2′-Bipyrrolidinyl is a high-purity, chiral bipyrrolidine compound, a key building block in asymmetric synthesis. Its value lies in its role as a privileged ligand and organocatalyst, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality chiral auxiliaries.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation and C-C bond formation.
• As an organocatalyst for enantioselective synthesis in pharmaceutical intermediate manufacturing.
• In the research and development of novel active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• For the synthesis of complex natural products and fine chemicals where stereocontrol is critical.
• In methodological development for academic and industrial research in organic and medicinal chemistry.
• As a precursor for the synthesis of more complex, tailored chiral catalyst systems.

Basic Information

Product Name	(R,R)-2,2′-Bipyrrolidinyl
CAS No.	137037-20-8
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	(R,R)-2,2'-Bipyrrolidine; (2R,2'R)-2,2'-Bipyrrolidine; (R,R)-2,2'-Diaminobipyrrolidine; (R,R)-Bipyrrolidine; (R,R)-2,2'-Bipyrrolidinyl dihydrochloride (salt form); (R,R)-BIPY; (2R,2'R)-2,2'-Bipyrrolidinyl; (R,R)-2,2'-Bipyrrolidin-1-yl
EINECS	Contact for details

Quality Control

Our (R,R)-2,2′-Bipyrrolidinyl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical development and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.