Description

2,4,5-Trifluoro-3-Methoxy-Benzoic Acid Methyl Ester is a high-purity fluorinated aromatic building block of significant commercial importance. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the life sciences and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly those containing a multi-fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides where the trifluoromethoxy and ester functionalities are essential.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of electron-deficient aromatic units for organic semiconductors and OLED materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and introducing fluorine atoms into target molecules.

Basic Information

Product Name	2,4,5-Trifluoro-3-Methoxy-Benzoic Acid Methyl Ester
CAS No.	136897-64-8
Molecular Formula	C9H7F3O3
Molecular Weight	220.14 g/mol
Synonyms	Methyl 2,4,5-Trifluoro-3-Methoxybenzoate; 2,4,5-Trifluoro-3-Methoxybenzoic Acid Methyl Ester; Benzoic acid, 2,4,5-trifluoro-3-methoxy-, methyl ester; 3-Methoxy-2,4,5-trifluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-3-Methoxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.