Description

(-)-2-β-Carbomethoxy-3-β-(Iodophenyl)Tropane is a high-purity, specialized tropane alkaloid derivative of significant interest in advanced research and development. This compound serves as a critical intermediate and reference standard in the synthesis and study of potent pharmacological agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on neuroscience and receptor-binding studies.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel central nervous system (CNS) targeting compounds.
• Neuroscience Studies: Used as a reference standard and tool compound in receptor binding assays and pharmacological profiling.
• Analytical Chemistry: Serves as a certified reference material (CRM) for method development and validation in HPLC and LC-MS analysis.
• Fine Chemical Synthesis: A versatile building block for the preparation of more complex, structurally related tropane derivatives.
• Biochemical Research: Employed in studies investigating neurotransmitter transporter mechanisms and interactions.

Basic Information

Product Name	(-)-2-β-Carbomethoxy-3-β-(Iodophenyl)Tropane
CAS No.	136794-86-0
Molecular Formula	C16H20INO2
Molecular Weight	369.24 g/mol
Synonyms	(-)-2β-Carbomethoxy-3β-(4-iodophenyl)tropane; β-CIT; RTI-55; 2β-Carbomethoxy-3β-(4-iodophenyl)tropane; (1R,2S,3S,5S)-3-(4-Iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester; Nor-β-CIT; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (-)-2-β-Carbomethoxy-3-β-(Iodophenyl)Tropane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.