Description

D-Ribo-Hexitol, 3-Deoxy-2-o-Methyl-5,6-o-(1-Methylethylidene)-1-C-Phenyl-4-o-(Phenylmethyl)-, (1S)- is a sophisticated, stereochemically defined carbohydrate derivative, specifically a protected and modified hexitol. This compound matters as a high-value chiral building block and key synthetic intermediate for the development of novel pharmaceuticals and bioactive molecules. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams focused on nucleoside analogs, glycosidase inhibitors, and complex carbohydrate chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of nucleoside analogs and antiviral/antitumor drug candidates.
• Glycosidase Inhibitor Research: Used as a scaffold for developing potential therapeutic agents targeting metabolic disorders.
• Carbohydrate Chemistry: Acts as a protected and functionalized starting material for the synthesis of complex oligosaccharides and glycoconjugates.
• Chiral Pool Synthesis: Provides a source of defined stereochemistry for the asymmetric synthesis of natural products and specialty chemicals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms and carbohydrate-protein interactions.
• Process Development: Employed in route scouting and optimization for the scalable production of advanced pharmaceutical ingredients (APIs).

Basic Information

Product Name	D-Ribo-Hexitol, 3-Deoxy-2-o-Methyl-5,6-o-(1-Methylethylidene)-1-C-Phenyl-4-o-(Phenylmethyl)-, (1S)-
CAS No.	136781-83-4
Molecular Formula	C23H28O5
Molecular Weight	384.47 g/mol
Synonyms	(1S)-3-Deoxy-2-O-methyl-5,6-O-(1-methylethylidene)-1-C-phenyl-4-O-(phenylmethyl)-D-ribo-hexitol; 1-C-Phenyl-4-O-benzyl-3-deoxy-2-O-methyl-5,6-O-isopropylidene-D-ribo-hexitol; 1-C-Phenyl-4-O-benzyl-3-deoxy-2-O-methyl-5,6-O-(1-methylethylidene)-D-ribo-hexitol; Protected D-ribo-Hexitol Derivative; Chiral Benzyl-Protected Hexitol; Isopropylidene Acetal of Modified Hexitol
EINECS	Contact for details

Quality Control

Our D-Ribo-Hexitol derivative is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full characterization data (NMR, MS, IR) are provided to guarantee traceability and support your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.