Description

Dl-Serine (3-13C) is a stable isotope-labeled analog of the amino acid serine, specifically enriched with carbon-13 at the 3-position. This compound is an essential tool for advanced research requiring precise metabolic and biochemical pathway tracing. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications such as metabolic flux analysis, protein NMR spectroscopy, and the development of labeled diagnostic agents.

Application

• Metabolic Flux Analysis (MFA): Used as a tracer to study central carbon metabolism and quantify intracellular reaction rates in biological systems.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a crucial probe for protein structure determination, dynamics studies, and biomolecular interaction analysis.
• Mass Spectrometry (MS) Standards: Acts as an internal standard for the accurate quantification of serine and related metabolites in complex biological samples via LC-MS or GC-MS.
• Pharmaceutical Research & Development: Employed in the synthesis of isotopically labeled drug candidates for pharmacokinetic (ADME) studies and biomarker discovery.
• Nutritional Science Research: Used in studies investigating amino acid metabolism, protein synthesis, and nutritional labeling in vivo.
• Diagnostic Agent Development: A key precursor in the creation of advanced positron emission tomography (PET) tracers and other diagnostic imaging compounds.

Basic Information

Product Name	Dl-Serine (3-13C)
CAS No.	135575-84-7
Molecular Formula	C313CH7NO3
Molecular Weight	106.09 g/mol (for 13C1 isotopologue)
Synonyms	(±)-Serine-3-13C; DL-Serine-3-13C; Serine (3-13C, DL-); 3-13C-DL-Serine; 2-Amino-3-13C-hydroxypropanoic acid; 3-13C-labeled DL-Serine; (±)-2-Amino-3-13C-3-hydroxypropionic acid; 3-Carbon-13 labeled DL-Serine
EINECS	Contact for details

Quality Control

Our Dl-Serine (3-13C) is manufactured under strict quality control protocols to ensure high isotopic and chemical purity, essential for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Isotopic Purity	≥ 99% (by MS)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.