Description

2,4,6-Tris(Trifluoromethyl)Benzoyl Chloride is a highly fluorinated aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the reactive benzoyl chloride group and the electron-withdrawing, lipophilic trifluoromethyl substituents, which impart exceptional properties to final compounds. This specialty intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs to modulate potency, lipophilicity, and metabolic profile.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl groups improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to improved performance and stability.
• Polymer & Resin Modification: Employed to introduce fluorinated aromatic units into polymer chains, enhancing chemical resistance, thermal stability, and surface properties of high-performance materials.
• Organic Synthesis & Catalysis: A versatile reagent for Friedel-Crafts acylation and other coupling reactions to create complex, fluorinated aromatic structures for research and development.
• Dye & Pigment Industry: Used in the synthesis of specialized fluorinated dyes and pigments that offer superior lightfastness and unique chromatic properties.

Basic Information

Product Name	2,4,6-Tris(Trifluoromethyl)Benzoyl Chloride
CAS No.	135130-97-1
Molecular Formula	C10H2ClF9O
Molecular Weight	344.56 g/mol
Synonyms	2,4,6-Tris(trifluoromethyl)benzoyl chloride; Benzoyl chloride, 2,4,6-tris(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoromesitoyl chloride; Mesitoyl chloride, 2,4,6-tris(trifluoromethyl)-; Hexafluoromesitoyl chloride; 2,4,6-(CF3)3C6H2COCl; Perfluoromesitoyl chloride (common name)
EINECS	Contact for details

Quality Control

Our 2,4,6-Tris(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.