Description

3,4-Premercapturic Acid CAS NO 134958-24-0 is a specialized mercapturic acid derivative, serving as a key biomarker and analytical reference standard in toxicological and metabolic studies. Its value lies in its critical role for the accurate detection and quantification of specific chemical exposures in biological systems. This compound is essential for research institutions, contract research organizations (CROs), and diagnostic manufacturers focused on occupational health, environmental monitoring, and pharmaceutical metabolism.

Application

• Biomarker Analysis: Used as a certified reference material for the precise quantification of specific metabolite levels in urine or blood samples in exposure studies.
• Toxicological Research: Serves as a critical standard in research investigating the metabolic pathways and biological fate of industrial chemicals and environmental pollutants.
• Occupational Health & Safety Monitoring: Enables the development and validation of analytical methods for biomonitoring programs to assess workplace chemical exposure.
• Pharmacokinetic/ADME Studies: Employed in pharmaceutical research to study the absorption, distribution, metabolism, and excretion (ADME) of drug candidates, particularly those metabolized via mercapturic acid pathways.
• Diagnostic Kit Development: Acts as a key component in the calibration and quality control of diagnostic assays and kits designed for exposure biomarker detection.
• Regulatory Compliance & Safety Testing: Supports testing required for regulatory submissions and safety evaluations by providing a traceable analytical standard.

Basic Information

Product Name	3,4-Premercapturic Acid
CAS No.	134958-24-0
Molecular Formula	C9H13NO5S
Molecular Weight	247.27 g/mol
Synonyms	N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine; 3,4-DHBMAA; 1-Mercapturic Acid-3,4-Butanediol; Pre-Mercapturic Acid Metabolite; N-Acetyl-S-(3,4-dihydroxybutyl)cysteine; L-Cysteine, N-acetyl-S-(3,4-dihydroxybutyl)-; 3,4-Dihydroxybutyl Mercapturic Acid
EINECS	Contact for details

Quality Control

Every batch of our 3,4-Premercapturic Acid is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the rigorous demands of research and diagnostic applications. A detailed Certificate of Analysis (COA) including results for assay, related substances, and identification is supplied with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.