Description

2'-Fluoro-2',3'-Dideoxyinosine is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the discovery of nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of antiviral and antineoplastic drugs.
• Biochemical Research: Used as a reference standard and probe in enzymatic studies and metabolic pathway analysis.
• Antiviral Agent Development: Serves as a core scaffold for creating novel nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral compounds.
• Oncology Research: Investigated for its potential as a chemotherapeutic agent or as a component of targeted cancer therapies.
• Process Chemistry: Employed in route scouting and scale-up synthesis for active pharmaceutical ingredient (API) manufacturing.
• Academic Research: Utilized in universities and research labs for studying nucleoside chemistry, structure-activity relationships (SAR), and drug resistance mechanisms.

Basic Information

Product Name	2'-Fluoro-2',3'-Dideoxyinosine
CAS No.	134892-26-5
Molecular Formula	C10H11FN4O3
Molecular Weight	254.22 g/mol
Synonyms	2'-F-ddI; 2'-Fluoro-2',3'-dideoxyinosine; 9-[(2R,5S)-5-Fluoro-2,5-dihydro-2-furanyl]-9H-purin-6-amine; 2'-F-2',3'-ddI; 2'-Fluoro-ddI; 2'-F-dideoxyinosine; 9-[(2R,5S)-5-Fluoro-2,5-dihydro-2-furanyl]-6-aminopurine
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-2',3'-Dideoxyinosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.