Description

5-Fluoroisatoic Anhydride is a specialized fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key precursor for introducing the 5-fluoro-isatoic acid moiety into target molecules, enabling the development of compounds with enhanced biological activity and physicochemical properties. This high-purity intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated quinazolinone and quinoline derivatives, which are scaffolds in various drug discovery projects.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or precursor for creating specialized fluorinated polymers and advanced organic materials with unique properties.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Fluoroisatoic Anhydride
CAS No.	134792-45-3
Molecular Formula	C8H4FNO3
Molecular Weight	181.12 g/mol
Synonyms	5-Fluoroisatoic Anhydride; 5-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione; 5-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione; 5-Fluoro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione; 5-Fluoroisatoic Acid Anhydride; 5-Fluoro-1,3-dihydro-2H-3,1-benzoxazine-2,4-dione
EINECS	Contact for details

Quality Control

Our 5-Fluoroisatoic Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.