Description

(S)-4-(1-Hydroxyethyl) Benzoic Acid Methyl Ester is a high-value chiral intermediate characterized by its benzoic acid ester core and a stereospecific hydroxyethyl side chain. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced fine chemicals, where optical purity is paramount. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutics and high-performance materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, optically active pesticides and herbicides.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of specialty organic electronic materials and liquid crystal displays (LCDs).
• Asymmetric Catalysis Research: Employed as a standard or ligand precursor in academic and industrial research focused on chiral catalysis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance compounds, flavors, and other high-value specialty chemicals.
• Polymer Modification: Utilized to introduce chiral benzoate moieties into polymer chains to modify physical and optical properties.

Basic Information

Product Name	(S)-4-(1-Hydroxyethyl) Benzoic Acid Methyl Ester
CAS No.	134615-20-6
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(S)-Methyl 4-(1-Hydroxyethyl)benzoate; Methyl (S)-4-(1-Hydroxyethyl)benzoate; (S)-Methyl 4-(α-Hydroxyethyl)benzoate; Benzoic acid, 4-(1-hydroxyethyl)-, methyl ester, (S)-; (S)-(-)-Methyl 4-(1-Hydroxyethyl)benzoate; (S)-HMEB; (S)-Methyl p-(1-hydroxyethyl)benzoate
EINECS	Contact for details

Quality Control

Our (S)-4-(1-Hydroxyethyl) Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.