Description

3-Amino-2,5,6-Trifluorobenzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and amino substitution pattern makes it indispensable for creating compounds with tailored electronic and steric properties. This intermediate is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component for synthesizing fluorinated liquid crystals, essential for high-performance displays.
• Organic Electronic Materials: Building block for electron-transport materials and semiconductors used in OLEDs and organic photovoltaics.
• Complex Ligand Synthesis: Used to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Dye & Pigment Intermediate: Imparts light-fastness and chemical resistance in the production of advanced colorants.

Basic Information

Item	Detail
Product Name	3-Amino-2,5,6-Trifluorobenzoic Acid
CAS No.	133622-65-8
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	2,5,6-Trifluoro-3-aminobenzoic Acid; Benzoic acid, 3-amino-2,5,6-trifluoro-; 3-Amino-2,5,6-trifluorobenzoic acid; 2,5,6-Trifluoro-m-aminobenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-2,5,6-Trifluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to support your project.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.