Description

2-(4-Fluorophenyl)Imidazo[1,2-A]Pyridine-8-Carboxylic Acid is a high-value heterocyclic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex fused-ring systems. Pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers need this material to develop next-generation drugs and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging its unique fused-ring structure for biological activity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring new chemical entities.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and assay development.
• Custom Synthesis: A starting point for contract manufacturing organizations (CMOs) producing bespoke compounds for client-specific projects.

Basic Information

Product Name	2-(4-Fluorophenyl)Imidazo[1,2-A]Pyridine-8-Carboxylic Acid
CAS No.	133427-95-9
Molecular Formula	C14H9FN2O2
Molecular Weight	256.23 g/mol
Synonyms	8-Carboxy-2-(4-fluorophenyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-8-carboxylic acid, 2-(4-fluorophenyl)-; 2-(p-Fluorophenyl)imidazo[1,2-a]pyridine-8-carboxylic acid; 133427-95-9; 2-(4-Fluorophenyl)-1H-imidazo[4,5-c]pyridine-7-carboxylic acid (related isomer); 2-(4-Fluorophenyl)imidazopyridine-8-carboxylic acid; 8-Imidazo[1,2-a]pyridinecarboxylic acid, 2-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)Imidazo[1,2-A]Pyridine-8-Carboxylic Acid is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and commercial-scale synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.