Description

Lesopitron is a selective 5-HT1A receptor antagonist with significant research and pharmaceutical development interest. This compound is a critical intermediate and reference standard in the synthesis and study of novel anxiolytic and antidepressant agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) for preclinical and analytical applications.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel therapeutic agents targeting serotonin receptors.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in API manufacturing.
• Preclinical Studies: Employed in pharmacological and toxicological research to investigate mechanisms of action related to anxiety and depression.
• Chemical Synthesis: Acts as a building block for medicinal chemists to create new chemical entities with potential CNS activity.
• Academic Research: Utilized in university and institutional labs for neurochemical and behavioral studies.

Basic Information

Product Name	Lesopitron
CAS No.	132449-89-9
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	Lesopitron; 2-[4-[4-(4-Chlorophenyl)-1-piperazinyl]butyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one; BAY v 7819; BAY-v-7819; BAY v 7819; BAY-v 7819; EMD-49980; EMD 49980
EINECS	Contact for details

Quality Control

Our Lesopitron is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, NMR, and MS. We support compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.