Description

1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2,4-Triazole-3-Carboximidamide is a high-purity nucleoside analog with significant potential in advanced pharmaceutical research and development. This compound matters as a sophisticated building block for the synthesis of novel antiviral and anticancer agents, offering researchers a critical tool for probing biological pathways and developing targeted therapies. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the discovery of nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside metabolism and related cellular processes.
• Antiviral Agent Development: A core scaffold for research into treatments for viral infections, leveraging its modified nucleoside structure.
• Oncology Research: Investigated for its potential to be incorporated into prodrugs or targeted therapies designed to disrupt DNA/RNA synthesis in cancer cells.
• Molecular Biology: Can be utilized in the synthesis of labeled probes or modified oligonucleotides for diagnostic and research applications.
• Chemical Synthesis: Acts as a chiral building block for the preparation of more complex, biologically active molecules in medicinal chemistry programs.

Basic Information

Product Name	1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2,4-Triazole-3-Carboximidamide
CAS No.	132425-32-2
Molecular Formula	C9H14N4O5
Molecular Weight	258.23 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboximidamide; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamidine; 3-Carbamimidoyl-1-β-D-ribofuranosyl-1H-1,2,4-triazole; Ribofuranosyltriazolecarboximidamide; 1,2,4-Triazole-3-carboximidamide, 1-β-D-ribofuranosyl-; (2R,3R,4R,5R)-2-(3-Carbamimidoyl-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
EINECS	Contact for details

Quality Control

Our 1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-1,2,4-Triazole-3-Carboximidamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and comprehensive identification tests. Certificates of Analysis (COA) detailing all specifications and results are provided to ensure full traceability and compliance with your research-grade or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.