Description

(3Ar,4R,6R,6As)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxole-4-Methanol is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is critical for producing enantiomerically pure active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing organizations in the pharmaceutical and fine chemical sectors, particularly those developing nucleoside analogs and other complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of antiviral and anticancer nucleoside analogs.
• Process Chemistry: Used in the research, development, and scale-up of new synthetic routes for complex molecules.
• Asymmetric Synthesis: Serves as a precursor or reagent in reactions requiring high stereoselectivity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where precise stereochemistry is mandatory.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and API production.
• Academic & Industrial R&D: Utilized in laboratories for methodological studies and the discovery of new bioactive compounds.

Basic Information

Product Name	(3Ar,4R,6R,6As)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxole-4-Methanol
CAS No.	132342-52-0
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	6-Amino-2,2-dimethyl-4H-cyclopenta-1,3-dioxole-4-methanol, (3aR,4R,6R,6aR)-rel-; 6-Amino-2,2-dimethyl-tetrahydro-4H-cyclopenta[1,3]dioxole-4-methanol; (3aR,4R,6R,6aR)-6-Amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-methanol; 1,2-O-Isopropylidene-α-D-allofuranose derivative; Chiral cyclopentane dioxole intermediate; Aminodioxole methanol derivative
EINECS	Contact for details

Quality Control

Our (3Ar,4R,6R,6As)-6-Aminotetrahydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxole-4-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.