Description

6H-Purin-6-One, 1,9-Dihydro-9-[Tetrahydro-5-(Hydroxymethyl)-2-Furanyl]-, (Cis)-(+-)- is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where its specific stereochemistry is essential for biological activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogue drugs targeting viral infections.
• Antiviral Drug Research: Used in the development of new therapeutic agents against a range of DNA and RNA viruses.
• Oncology Research: Serves as a scaffold for creating novel chemotherapeutic compounds that interfere with cancer cell DNA/RNA synthesis.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for nucleoside-metabolizing enzymes.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	6H-Purin-6-One, 1,9-Dihydro-9-[Tetrahydro-5-(Hydroxymethyl)-2-Furanyl]-, (Cis)-(+-)-
CAS No.	132339-54-9
Molecular Formula	C10H12N4O3
Molecular Weight	236.23 g/mol
Synonyms	(+)-cis-9-[Tetrahydro-5-(hydroxymethyl)-2-furanyl]guanine; cis-9-(Tetrahydro-5-(hydroxymethyl)-2-furanyl)guanine; cis-9-(Tetrahydro-5-(hydroxymethyl)furan-2-yl)guanine; cis-9-(5-Hydroxymethyltetrahydrofuran-2-yl)guanine; cis-9-(5-Hydroxymethyl-2-tetrahydrofuranyl)guanine; cis-9-(Tetrahydro-5-(hydroxymethyl)-2-furanyl)-9H-purin-6-amine; (+)-cis-9-(5-Hydroxymethyltetrahydrofuran-2-yl)guanine; cis-9-(5-Hydroxymethyltetrahydrofuran-2-yl)-9H-purin-6-amine
EINECS	Contact for details

Quality Control

Our 6H-Purin-6-One, 1,9-Dihydro-9-[Tetrahydro-5-(Hydroxymethyl)-2-Furanyl]-, (Cis)-(+-)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.