Description

(R)-(-)-4-Benzyl-3-Propionyl-2-Oxazolidinone is a high-purity chiral auxiliary and synthetic building block of significant importance in asymmetric organic synthesis. Its core value lies in enabling the stereoselective construction of complex molecules, ensuring high enantiomeric excess in final products. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over molecular chirality for developing active ingredients and advanced materials.

Application

• As a versatile chiral auxiliary in Evans aldol and related asymmetric reactions.
• For the stereoselective synthesis of pharmaceutical intermediates, including β-lactam antibiotics and protease inhibitors.
• In the preparation of agrochemicals where specific stereochemistry is required for biological activity.
• As a key building block in academic and industrial research for methodological development in organic chemistry.
• For the production of fine chemicals and specialty materials with defined optical properties.
• In process chemistry for the scalable, enantioselective manufacture of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(R)-(-)-4-Benzyl-3-Propionyl-2-Oxazolidinone
CAS No.	131685-53-5
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	(R)-4-Benzyl-3-propionyl-2-oxazolidinone; (R)-(-)-4-Benzyl-3-propionyloxazolidin-2-one; (R)-N-Propionyl-4-benzyl-2-oxazolidinone; Evans Auxiliary (Propionyl); (R)-4-Benzyl-3-(1-oxopropyl)-2-oxazolidinone; (R)-3-Propionyl-4-benzyloxazolidin-2-one; (R)-N-Propionyl-4-phenylmethyl-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (R)-(-)-4-Benzyl-3-Propionyl-2-Oxazolidinone is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.