Description

(1S,2S)-(-)-3-Exo-Hydroxy-2,10-Camphorsultam is a high-value, enantiomerically pure chiral auxiliary and building block derived from camphor. This compound is critically important for its ability to induce high stereoselectivity in a wide range of organic transformations, particularly in asymmetric synthesis. It is an essential reagent for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over the three-dimensional architecture of complex molecules.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Employed to control the stereochemistry of aldol reactions, alkylations, Diels-Alder reactions, and other C-C bond-forming processes.
• Pharmaceutical Intermediate: Used in the research and development of enantiomerically pure active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Catalyst and Ligand Precursor: Serves as a starting material for the synthesis of novel chiral catalysts and ligands used in metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Applied in the production of chiral herbicides, fungicides, and pesticides where specific stereoisomers exhibit superior biological activity.
• Academic and Industrial R&D: A fundamental tool in methodological development for stereoselective synthesis within university laboratories and corporate R&D centers.
• Resolution Agent: Can be utilized in the kinetic resolution or classical resolution of racemic mixtures of acids, alcohols, or amines.

Basic Information

Product Name	(1S,2S)-(-)-3-Exo-Hydroxy-2,10-Camphorsultam
CAS No.	130748-66-2
Molecular Formula	C₁₀H₁₅NO₃S
Molecular Weight	229.30 g/mol
Synonyms	(1S,2S)-3-endo-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane-2-sulfonamide; (-)-3-exo-Hydroxycamphorsultam; (1S,2S)-(-)-3-Hydroxy-2,10-camphorsultam; (1S,2S)-3-Hydroxycamphor-10,2-sultam; Camphorsultam derivative; Chiral camphorsultam auxiliary; (1S,2S)-3-exo-Hydroxy-2,10-camphorsultam
EINECS	Contact for details

Quality Control

Our (1S,2S)-(-)-3-Exo-Hydroxy-2,10-Camphorsultam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. All products undergo rigorous analytical testing, including chiral HPLC, to confirm identity, purity, and optical rotation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]²⁰D	-30° to -35° (c=1 in CHCl₃)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.