Description

(R)-T-Butyl Glycidyl Ether is a high-value chiral epoxide building block, essential for the synthesis of enantiomerically pure compounds. Its primary commercial value lies in its role as a key intermediate for introducing the tert-butyl glycidyl moiety in a stereoselective manner, which is critical for developing advanced pharmaceuticals and fine chemicals. This product is particularly needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and functional materials with specific chiral configurations.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A crucial building block for the production of enantiomerically pure active pharmaceutical ingredients (APIs), including β-blockers and other cardiovascular drugs.
• Agrochemical Precursor: Used in the research and development of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical and Specialty Polymer Production: Employed to introduce chiral epoxide functionalities into complex molecules and polymers for advanced material science applications.
• Resolution Agent: Can be utilized in the kinetic resolution of racemic mixtures or as a chiral auxiliary in synthetic organic chemistry.

Basic Information

Product Name	(R)-T-Butyl Glycidyl Ether
CAS No.	130232-98-3
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(R)-(-)-tert-Butyl Glycidyl Ether; (R)-1,2-Epoxy-3-tert-butoxypropane; (R)-2-[(tert-Butoxy)methyl]oxirane; (R)-Tertiary Butyl Glycidyl Ether; (R)-TBGE; (R)-Glycidyl tert-Butyl Ether; (2R)-2-[(2-Methylpropan-2-yl)oxymethyl]oxirane; (R)-(-)-TBGE
EINECS	Contact for details

Quality Control

Our (R)-T-Butyl Glycidyl Ether is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, purity, and optical rotation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Optical Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.