Description

(S)-(-)-1,1,1-Trifluorooctan-2-Ol is a high-value, chiral fluorinated alcohol building block, essential for introducing trifluoromethyl-bearing stereocenters into complex molecules. Its precise stereochemistry and unique fluorine substitution pattern make it a critical intermediate for developing advanced materials and pharmaceuticals with enhanced metabolic stability and bioavailability. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl group for improved lipophilicity and metabolic resistance.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in advanced electronic displays and organic light-emitting diodes, improving performance and stability.
• Asymmetric Catalyst Ligand Synthesis: Employed in the preparation of chiral ligands for transition metal catalysis, enabling highly enantioselective transformations.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and optical characteristics.
• Fluorine-19 NMR Spectroscopy: Can be used as a standard or probe molecule in NMR studies due to the distinct signal of its trifluoromethyl group.

Basic Information

Item	Detail
Product Name	(S)-(-)-1,1,1-Trifluorooctan-2-Ol
CAS No.	129443-08-9
Molecular Formula	C8H15F3O
Molecular Weight	184.20 g/mol
Synonyms	(S)-1,1,1-Trifluoro-2-octanol; (S)-(-)-1,1,1-Trifluoro-2-octanol; (2S)-1,1,1-Trifluorooctan-2-ol; (S)-Trifluorooctanol; (S)-2-Octanol, 1,1,1-trifluoro-; 1,1,1-Trifluoro-(S)-2-octanol; (S)-α-(Trifluoromethyl)heptyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (S)-(-)-1,1,1-Trifluorooctan-2-Ol is produced under strict quality management protocols. We guarantee high chemical and enantiomeric purity, verified through advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.