Description

Rivastigmine Tartrate CAS NO 129101-54-8 is a high-purity, non-competitive reversible acetylcholinesterase inhibitor used as the active pharmaceutical ingredient (API) in the formulation of medications. This compound is critical for the treatment of mild to moderate dementia associated with Alzheimer's disease and Parkinson's disease. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in neurological therapeutics.

Application

• Primary Active Pharmaceutical Ingredient (API) in capsule and oral solution formulations.
• Key component in transdermal patch systems for controlled drug delivery.
• Reference standard for analytical method development and validation in quality control laboratories.
• Raw material for preclinical and clinical research studies in neurodegenerative disorders.
• Intermediate in the synthesis of novel cholinesterase inhibitor derivatives.
• Used in stability studies and formulation development for generic drug applications.

Basic Information

Product Name	Rivastigmine Tartrate
CAS No.	129101-54-8
Molecular Formula	C14H22N2O2 • C4H6O6
Molecular Weight	400.43 g/mol
Synonyms	Rivastigmine Hydrogen Tartrate; (S)-3-[1-(Dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate Tartrate; Exelon (trade name); SDZ ENA 713; ENA 713; Rivastigmine Bitartrate; Rivastigmine (2R,3R)-2,3-Dihydroxybutanedioate; (S)-N-Ethyl-N-methyl-3-[1-(dimethylamino)ethyl]phenyl carbamate (2R,3R)-tartrate
EINECS	Contact for details

Quality Control

Our Rivastigmine Tartrate is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to meet stringent pharmacopeial standards, including identification, purity, assay, and impurity profile controls. A Certificate of Analysis (COA) is provided with each batch, detailing results for all specified tests to ensure compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	+8.0° to +12.0° (c = 1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.