Description

(±)17-Hete CAS NO 128914-47-6 is a high-purity synthetic hydroxy eicosatetraenoic acid (HETE) derivative, a key intermediate in lipid signaling research. This compound is critical for studying the biochemical pathways and physiological roles of eicosanoids in inflammation, cell proliferation, and vascular biology. It is an essential tool for pharmaceutical R&D, academic research, and the development of analytical standards in the life sciences sector.

Application

• Biochemical Research: Used as a reference standard and precursor in the study of lipoxygenase and cytochrome P450 metabolic pathways.
• Pharmaceutical Development: Serves as a critical intermediate for synthesizing novel compounds targeting inflammatory and cardiovascular diseases.
• Analytical Chemistry: Employed as a high-purity standard for method development and validation in HPLC, LC-MS, and GC-MS analyses.
• Cell Biology Studies: Applied in vitro to investigate the effects of eicosanoids on cell signaling, migration, and apoptosis.
• Enzyme Activity Assays: Utilized as a substrate or inhibitor in assays for lipoxygenase and related enzymes.

Basic Information

Product Name	(±)17-Hete
CAS No.	128914-47-6
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	(±)17-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid; 17-HETE; 17-Hydroxyeicosatetraenoic acid; rac-17-HETE; 17(S/R)-HETE; 17-HETE racemic mixture; 5Z,8Z,11Z,14Z-Eicosatetraenoic acid, 17-hydroxy-
EINECS	Contact for details

Quality Control

Our (±)17-Hete is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.