Description

Trisphenyl(3,3,3-Trifluoroprop-1-Yl)Phosphonium Iodide is a specialized organophosphonium salt that serves as a versatile reagent in advanced organic synthesis. Its primary value lies in its role as a Wittig-type olefination reagent, enabling the efficient introduction of the 3,3,3-trifluoroprop-1-yl group to construct fluorinated olefins, which are critical motifs in pharmaceuticals and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate trifluoromethylated alkenes into their target molecules.

Application

• Synthesis of Fluorinated Pharmaceuticals: Key intermediate for constructing trifluoromethyl-substituted alkenes, a privileged scaffold in drug discovery for improving metabolic stability and lipophilicity.
• Agrochemical Active Ingredient Development: Used to create novel fluorinated analogs of pesticides and herbicides, enhancing their biological activity and environmental persistence.
• Advanced Material Precursors: Building block for fluorinated liquid crystals, organic semiconductors, and polymers with unique electronic and surface properties.
• Organic Synthesis Reagent: Employed in Wittig and related olefination reactions to install the CF3-CH=CH- moiety under mild conditions.
• R&D and Process Chemistry: Critical reagent for laboratory-scale research and scale-up processes in fine chemical and custom synthesis manufacturing.
• Fluorine Chemistry Research: A valuable tool for academic and industrial researchers exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	Trisphenyl(3,3,3-Trifluoroprop-1-Yl)Phosphonium Iodide
CAS No.	128622-15-1
Molecular Formula	C27H21F3IP
Molecular Weight	584.22 g/mol
Synonyms	(3,3,3-Trifluoropropyl)triphenylphosphonium iodide; Triphenyl(3,3,3-trifluoropropyl)phosphonium iodide; 3,3,3-Trifluoropropyltriphenylphosphonium iodide; Phosphonium, (3,3,3-trifluoropropyl)triphenyl-, iodide (1:1); (3,3,3-Trifluoroprop-1-yl)triphenylphosphonium iodide; Trisphenyl(3,3,3-trifluoropropyl)phosphonium iodide
EINECS	Contact for details

Quality Control

Our Trisphenyl(3,3,3-Trifluoroprop-1-Yl)Phosphonium Iodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 31P), HPLC, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity synthetic reagents in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.