Description

1-(2,3-Dideoxy-2-Fluoropentofuranosyl)-5-Fluorocytosine is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate or potential active pharmaceutical ingredient (API) for novel antiviral and anticancer therapeutics. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of next-generation nucleoside-based drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Investigated for its potential activity against a range of viral targets due to its modified sugar and base moieties.
• Oncology Research: Used in the development of chemotherapeutic agents that target DNA/RNA synthesis in cancer cells.
• Biochemical Tool: Serves as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of specialty active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-(2,3-Dideoxy-2-Fluoropentofuranosyl)-5-Fluorocytosine
CAS No.	128496-09-3
Molecular Formula	C9H11F2N3O3
Molecular Weight	247.20 g/mol
Synonyms	2'-Fluoro-2',3'-dideoxy-5-fluorocytidine; 2'-F-ddFCyd; 1-((2R,5S)-5-(Hydroxymethyl)-2-fluorotetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-(2-fluoro-2,3-dideoxy-β-D-*erythro*-pentofuranosyl)cytosine; 2'-Fluoro-2',3'-dideoxy-5-fluorocytidine; FCddC; β-2'-F-2',3'-dd-5-FC
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dideoxy-2-Fluoropentofuranosyl)-5-Fluorocytosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.