Description

Deoxyspergualin (Hydrochloride) is a synthetic derivative of the natural product spergualin, functioning as a potent immunosuppressive agent. This compound is critical for research and development in the fields of immunology and transplant medicine, where precise modulation of the immune response is required. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in developing novel therapeutics for autoimmune diseases and organ rejection.

Application

• Immunosuppressive Research: A key tool compound for studying T-cell and B-cell function, cytokine production, and autoimmune disease mechanisms in preclinical models.
• Transplant Medicine R&D: Investigated for its potential to prevent graft-versus-host disease (GvHD) and organ transplant rejection.
• Oncology Research: Explored for its anti-proliferative effects and potential role in cancer immunotherapy protocols.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Pathway Studies: Used to investigate intracellular signaling pathways related to immune cell activation and apoptosis.
• API Intermediate: Acts as a critical synthetic intermediate in the production of more complex immunosuppressive drug candidates.

Basic Information

Product Name	Deoxyspergualin (Hydrochloride)
CAS No.	128488-79-9
Molecular Formula	C17H37N7O4 • HCl
Molecular Weight	464.0 g/mol
Synonyms	15-Deoxyspergualin Hydrochloride; DSG HCl; Gusperimus Hydrochloride; (-)-15-Deoxyspergualin Hydrochloride; 1-Amino-19-guanidino-11-hydroxy-4,9,12-triazanonadecane-10,13-dione Hydrochloride; Spanidin; NKT-01; (1S,11S,12S,15S)-15-Deoxyspergualin Hydrochloride
EINECS	Contact for details

Quality Control

Our Deoxyspergualin (Hydrochloride) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality guidelines to support our global clientele in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.