Description

(S)-(+)-(2-Methylacryloyl)-2,10-Camphorsultam CAS NO 128441-99-6 is a high-purity, enantiomerically pure chiral auxiliary and building block derived from camphorsultam. This compound matters for its critical role in facilitating highly stereoselective chemical transformations, particularly in asymmetric synthesis. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require precise control over molecular chirality to develop active ingredients and functional molecules.

Application

• Asymmetric Synthesis: Employed as a versatile chiral auxiliary for the enantioselective synthesis of α-substituted carbonyl compounds, carboxylic acids, and amines.
• Pharmaceutical Intermediates: Key building block in the research and development of chiral active pharmaceutical ingredients (APIs), enabling the production of single-enantiomer drugs.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure herbicides, fungicides, and pesticides where biological activity is often specific to one stereoisomer.
• Catalyst and Ligand Preparation: Serves as a precursor for the synthesis of novel chiral catalysts and ligands used in homogeneous catalysis.
• Material Science Research: Utilized in the development of chiral polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Process Chemistry: A valuable tool in academic laboratories and scale-up facilities for method development and optimization of stereocontrolled reactions.

Basic Information

Product Name	(S)-(+)-(2-Methylacryloyl)-2,10-Camphorsultam
CAS No.	128441-99-6
Molecular Formula	C₁₄H₂₁NO₄S
Molecular Weight	299.39 g/mol
Synonyms	(S)-(+)-N-(2-Methyl-1-oxo-2-propen-1-yl)-2,10-camphorsultam; (S)-N-Methacryloylcamphorsultam; (S)-3-[(2-Methylprop-2-enoyl)amino]-1,7,7-trimethylbicyclo[2.2.1]heptane-2-sulfonic acid 1,1-dioxide; (S)-N-Methacryloyl-10-camphorsulfonamide; (S)-N-Methacryloyl-10-camphorsultam; (S)-N-Methacryloylcamphorsulfonamide; Evans Chiral Auxiliary Derivative; Camphorsultam Methacrylate
EINECS	Contact for details

Quality Control

Our (S)-(+)-(2-Methylacryloyl)-2,10-Camphorsultam is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity, which is critical for asymmetric synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity (HPLC), chemical purity, and identity confirmation. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.