Description

2,4,5-Trifluoro-3-Hydroxybenzoic Acid Ethyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique trifluoro-hydroxy substitution pattern makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where fluorine atoms improve efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Electronic Materials: Intermediate in the development of fluorinated organic semiconductors and electron-transport materials.
• Complex Ligand Synthesis: Used to create specialized fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Dye & Pigment Production: Acts as a starting material for synthesizing dyes with improved lightfastness and chemical resistance.

Basic Information

Product Name	2,4,5-Trifluoro-3-Hydroxybenzoic Acid Ethyl Ester
CAS No.	128426-84-6
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	Ethyl 2,4,5-Trifluoro-3-hydroxybenzoate; 3-Hydroxy-2,4,5-trifluorobenzoic Acid Ethyl Ester; Benzoic acid, 2,4,5-trifluoro-3-hydroxy-, ethyl ester; 2,4,5-Trifluoro-3-hydroxy-benzoic acid ethyl ester; Ethyl 3-hydroxy-2,4,5-trifluorobenzoate
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-3-Hydroxybenzoic Acid Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.