Description

Ethyl 4-(Trifluoromethyl)Cinnamate is a high-value fluorinated organic intermediate characterized by its cinnamate ester structure and trifluoromethyl group. This compound matters for its role in introducing lipophilicity and metabolic stability into target molecules, making it a critical building block in advanced synthesis. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display technologies.
• Polymer Modification: Incorporated into specialty polymers to alter surface properties, stability, and performance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and esterification processes to construct complex molecular architectures.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing unique aromatic compounds.

Basic Information

Product Name	Ethyl 4-(Trifluoromethyl)Cinnamate
CAS No.	128408-03-7
Molecular Formula	C12H11F3O2
Molecular Weight	244.21 g/mol
Synonyms	Ethyl (E)-3-[4-(Trifluoromethyl)phenyl]acrylate; (E)-Ethyl 3-(4-(Trifluoromethyl)phenyl)acrylate; 4-(Trifluoromethyl)cinnamic acid ethyl ester; trans-Ethyl 4-(Trifluoromethyl)cinnamate; Ethyl p-(Trifluoromethyl)cinnamate; 2-Propenoic acid, 3-[4-(trifluoromethyl)phenyl]-, ethyl ester, (E)-; Ethyl (E)-3-(4-Trifluoromethylphenyl)propenoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(Trifluoromethyl)Cinnamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.