Description

D-Alanine, n-L-Lysyl-, Labeled With Carbon-14 (9Ci) is a high-specific-activity, isotopically labeled derivative of a dipeptide, essential for advanced metabolic and pharmacokinetic research. This compound provides a critical tool for tracing biochemical pathways with high sensitivity and precision, enabling definitive studies in drug development and biochemistry. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions conducting sophisticated radiotracer experiments.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled precursor to study the metabolism and catabolism of lysyl-alanine dipeptides in vivo and in vitro.
• Drug Metabolism and Pharmacokinetics (DMPK): A vital tool for conducting Absorption, Distribution, Metabolism, and Excretion (ADME) studies of peptide-based therapeutics.
• Biochemical Research: Enables the investigation of enzyme mechanisms, peptide transport, and incorporation into larger proteins or biological structures.
• Pharmaceutical Development: Supports the development and validation of analytical methods (e.g., LC-MS/MS) for quantifying drugs and their metabolites.
• Environmental Fate Studies: Can be applied in specialized research to track the environmental breakdown of organic compounds containing similar structural motifs.

Basic Information

Item	Details
Product Name	D-Alanine, n-L-Lysyl-, Labeled With Carbon-14 (9Ci)
CAS No.	128262-80-6
Molecular Formula	C9H1914CN3O3 *
Molecular Weight	Contact for details
Synonyms	L-Lysyl-D-alanine-14C; [14C]-L-Lys-D-Ala; Carbon-14 Labeled L-Lysyl-D-alanine; D-Alanine, L-lysyl-, (carbon-14)-; Radiolabeled Lys-Ala dipeptide; (S)-2,6-Diamino-N-[(R)-1-hydroxyethylidene]hexanamide-14C; 9Ci C-14 L-Lys-D-Ala
EINECS	Contact for details

* Formula indicates position of Carbon-14 label; exact position is manufacturer-specific.

Quality Control

Every batch of our Carbon-14 labeled D-Alanine, n-L-Lysyl- is manufactured and analyzed under strict quality systems to ensure high radiochemical purity and specific activity. Production adheres to cGMP guidelines where applicable for radiopharmaceutical precursors. Comprehensive analysis includes verification of specific activity, radiochemical purity (by HPLC), and chemical identity. A detailed Certificate of Analysis (COA), documenting all release specifications and analytical results, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the primary container in a sealed secondary vessel with desiccant. Handle and store in accordance with all local and national regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Specific Activity	~9 Ci/mmol (Contact for exact value)
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 95%
Solvent (for solutions)	Specified per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.