Description

Escitalopram is the pure S-enantiomer of the selective serotonin reuptake inhibitor (SSRI) citalopram, offering enhanced pharmacological activity and a favorable side-effect profile. It is a critical active pharmaceutical ingredient (API) in the global manufacture of antidepressant medications. This high-purity compound is essential for pharmaceutical companies and research institutions developing and producing treatments for major depressive disorder and anxiety disorders. Consistent quality and reliable supply are paramount for ensuring the safety and efficacy of the final drug product.

Application

• Pharmaceutical API: Primary use as the active ingredient in antidepressant and anti-anxiety tablet and oral solution formulations.
• Generic Drug Manufacturing: Sourcing for the production of generic versions of Lexapro® and other escitalopram-based medications.
• Clinical Research: Utilization in preclinical and clinical studies for new central nervous system (CNS) therapeutics.
• Dosage Form Development: Used in R&D for developing novel drug delivery systems, such as controlled-release formulations.
• Reference Standard: Serves as a high-purity chemical reference standard for analytical testing and quality control laboratories.
• Finished Product Testing: Employed in analytical methods development and validation for drug product assay and impurity profiling.

Basic Information

Product Name	Escitalopram
CAS No.	128196-01-0
Molecular Formula	C20H21FN2O
Molecular Weight	324.39 g/mol
Synonyms	(S)-Citalopram; (S)-(+)-Citalopram; S-Citalopram; Escitalopramum; Lexapro (Brand Name); Lu-26-054; 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile, (S)-; Esertia
EINECS	Contact for details

Quality Control

Our Escitalopram CAS NO 128196-01-0 is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, chiral purity, and impurity profile analysis (including related substances and residual solvents) to ensure it meets stringent pharmacopeial standards. A Certificate of Analysis (COA) detailing all test results against specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥ 99.5%
Related Substances (HPLC)	Individual impurity: ≤ 0.10% Total impurities: ≤ 0.50%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.