Description

Diisopropyl (4S,5S)-1,3,2-Dioxathiolane-4,5-dicarboxylate 2,2-Dioxide is a high-purity, chiral sulfite derivative of diisopropyl tartrate. This compound serves as a critical chiral auxiliary and building block in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and advanced material sectors seeking to control stereochemistry with high fidelity.

Application

• Asymmetric Synthesis: Employed as a chiral ligand or auxiliary in catalytic reactions to induce enantioselectivity.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Development: Used in the research and production of chiral herbicides, fungicides, and insecticides.
• Catalyst Development: Serves as a precursor or component in the design of novel asymmetric catalysts.
• Material Science: Potential monomer or additive for creating polymers with specific optical or structural properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Diisopropyl (4S,5S)-1,3,2-Dioxathiolane-4,5-dicarboxylate 2,2-Dioxide
CAS No.	127854-45-9
Molecular Formula	C12H20O8S
Molecular Weight	324.35 g/mol
Synonyms	(4S,5S)-Diisopropyl 1,3,2-Dioxathiolane-4,5-dicarboxylate 2,2-Dioxide; Diisopropyl L-Tartrate Cyclic Sulfite; (4S,5S)-Diisopropyl Tartrate Cyclic Sulfite; L-(+)-Diisopropyl Tartrate Cyclic Sulfite; (4S,5S)-DIPT Sulfite; Chiral Diisopropyl Tartrate Sulfite Derivative; 1,3,2-Dioxathiolane-4,5-dicarboxylic acid, 2,2-dioxide, bis(1-methylethyl) ester, (4S,5S)-
EINECS	Contact for details

Quality Control

Our Diisopropyl (4S,5S)-1,3,2-Dioxathiolane-4,5-dicarboxylate 2,2-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided to guarantee reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.