Description

4-Methoxy-2-(Trifluoromethyl)Benzoic Acid is a versatile trifluoromethylated aromatic building block prized for its unique combination of electron-donating methoxy and electron-withdrawing trifluoromethyl groups. This structural motif is critical for modulating the physicochemical properties of advanced molecules, particularly in enhancing metabolic stability and lipophilicity. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a core component in the synthesis of fluorine-containing liquid crystals for display technologies.
• Organic Electronic Materials: Building block for electron-transport materials, organic semiconductors, and OLED components.
• Advanced Polymer Chemistry: Monomer or modifier for creating high-performance, specialty polymers with tailored thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and exploring new synthetic methodologies in academic and industrial R&D labs.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Benzoic Acid
CAS No.	127817-85-0
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2-Trifluoromethyl-4-methoxybenzoic acid; 4-Methoxy-2-(trifluoromethyl)benzoic acid; Benzoic acid, 4-methoxy-2-(trifluoromethyl)-; 4-Methoxy-α,α,α-trifluoro-o-toluic acid; 2-Carboxy-5-methoxybenzotrifluoride; 4-Methoxy-2-trifluoromethylbenzoic acid; 127817-85-0; 4-Methoxy-2-(trifluoromethyl)benzoic acid CAS NO 127817-85-0
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.