Description

(4R,5S)-(2,2-Dimethyl-5-Vinyl-1,3-Dioxolan-4-Yl)Methan-1-Ol is a high-value chiral building block and intermediate, characterized by its dioxolane-protected diol functionality and vinyl group. This compound matters for its role in the stereoselective synthesis of complex molecules, offering precise control over three-dimensional structure, which is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of antiviral agents, antibiotics, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the defined stereochemistry enhances efficacy and reduces environmental impact.
• Fine Chemical Production: Serves as a versatile building block for fragrances, flavors, and specialty polymers that benefit from its protected diol and reactive vinyl handle.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Material Science: Utilized in the synthesis of functionalized monomers for creating polymers with tailored properties.

Basic Information

Product Name	(4R,5S)-(2,2-Dimethyl-5-Vinyl-1,3-Dioxolan-4-Yl)Methan-1-Ol
CAS No.	127758-25-2
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(4R,5S)-4-(Hydroxymethyl)-2,2-dimethyl-5-vinyl-1,3-dioxolane; (4R-cis)-4-(Hydroxymethyl)-2,2-dimethyl-5-vinyl-1,3-dioxolane; 1,3-Dioxolane-4-methanol, 2,2-dimethyl-5-vinyl-, (4R,5S)-; (4R,5S)-2,2-Dimethyl-5-vinyl-1,3-dioxolane-4-methanol; (4R,5S)-4-(Hydroxymethyl)-2,2-dimethyl-5-vinyl-1,3-dioxolane; Chiral Dioxolane Alcohol; Vinyl Dioxolane Methanol
EINECS	Contact for details

Quality Control

Our (4R,5S)-(2,2-Dimethyl-5-Vinyl-1,3-Dioxolan-4-Yl)Methan-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.