Description

Cholestanol, 5,6-Epoxy-D7 is a high-purity, deuterium-labeled derivative of cholestanol, specifically designed for advanced analytical and research applications. This compound serves as a critical stable isotope-labeled internal standard for the precise quantification of cholesterol and its metabolites in complex biological matrices. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, clinical diagnostics, and life science sectors requiring high accuracy in mass spectrometry and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for cholesterol and oxysterol analysis.
• Metabolic Pathway Research: Tracing and studying cholesterol biosynthesis, metabolism, and related enzymatic pathways in biological systems.
• Clinical Diagnostics: Enabling accurate measurement of cholesterol metabolites in patient serum or plasma for disease biomarker research.
• Pharmaceutical R&D: Used in drug discovery and development programs targeting cholesterol-related disorders, such as cardiovascular diseases.
• Biochemical Assays: Employed in enzymatic assays and in-vitro studies to investigate lipid metabolism and regulation.
• Food & Nutraceutical Analysis: Potential application in the analysis of sterol content and authenticity verification in food products and supplements.

Basic Information

Product Name	Cholestanol, 5,6-Epoxy-D7
CAS No.	127684-06-4
Molecular Formula	C27H39D7O2
Molecular Weight	~403.7 g/mol
Synonyms	5,6α-Epoxycholestan-3β-ol-d7; 5α,6α-Epoxycholestanol-d7; (3β)-5,6α-Epoxycholestan-3-ol-d7; 5,6α-Epoxy-5α-cholestan-3β-ol-d7; Deuterated 5,6-Epoxycholestanol; Cholestane-3β,5α,6α-triol 5,6-cyclic ether-d7; Stable Isotope Labeled Cholestanol Epoxide
EINECS	Contact for details

Quality Control

Every batch of Cholestanol, 5,6-Epoxy-D7 is manufactured and tested under strict quality management systems to ensure the highest standards of purity and isotopic enrichment. Our products undergo rigorous quality testing, including NMR, HPLC, and MS analysis, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as indicated on the label/Certificate of Analysis. For long-term storage, consider storage at -20°C under an inert atmosphere. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by GC or HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.